Lung Cancer Survival and Functional Polymorphisms in MBL2, an Innate-Immunity Gene
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چکیده
منابع مشابه
Lung cancer survival and functional polymorphisms in MBL2, an innate-immunity gene.
BACKGROUND The relationship among chronic inflammation, innate immunity, and cancer is well established. Mannose-binding lectin (MBL) is a key player in innate immunity. Five polymorphisms in the promoter and first exon of the MBL2 gene alter the expression and function of MBL in humans and are associated with inflammation-related disease susceptibility. These five polymorphisms create six well...
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ژورنال
عنوان ژورنال: JNCI: Journal of the National Cancer Institute
سال: 2007
ISSN: 1460-2105,0027-8874
DOI: 10.1093/jnci/djm128